The "fifth base" of nucleic acids. Important because it fails to form specific pair bonds with the other bases. In transfer RNAs, this property is used in the anticodon to allow matching of a single tRNA to several codons. PCR performed with primers containing inosine tolerates a limited degree of mismatch between primer and template, useful when trying to clone homologous protein by using degenerate primers.

Dictionary of molecular biology. 2004.

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  • inosine — in o*sine ([i^]n [ o]*s[i^]n), n. (Chem.) A ribonucleoside ({C10H12N4O5}) found in meat and meat extracts, differing from adenosine in having a hydroxyl rather than an amine attached to the purine ring. It may be prepared from adenosine by the… …   The Collaborative International Dictionary of English

  • inosine — inosine. См. инозин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Inosine — drugbox IUPAC name = Inosine CAS number = 58 63 9 ATC prefix = D06 ATC suffix = BB05 ATC supplemental = ATC|G01|AX02 PubChem = 6021 DrugBank = EXPT02378 C=10|H=12|N=4|O=5 molecular weight = 268.229 g/mol bioavailability = protein bound =… …   Wikipedia

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  • Inosine diphosphate — Structure de l inosine diphosphate Général No CAS …   Wikipédia en Français

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  • Inosine pranobex — Général Nom IUPAC 9 [(2R,3R,4S,5R) 3,4 dihydroxy 5 (hydroxyméthyl)oxolan 2 yl] 3H purin 6 one : acide 4 acétamidobenzoïque : 1 (diméthylamino)p …   Wikipédia en Français

  • Inosine pranobex — IUPAC name 9 [(2R,3R,4S,5R) 3,4 dihydroxy 5 (hydroxymethyl)oxolan 2 yl] 3H purin 6 one …   Wikipedia

  • Inosine-5′-monophosphate dehydrogenase — (IMPDH) is an enzymne which salvages purines to make guanine in the human pathogen Cryptosporidium parvum. The C. parvum enzyme IMPDH differs enough from human IMPDH to serve as a drug target. [Chem. Biol. 15, 70 (2008)] …   Wikipedia

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